Ingredient profile
6-HYDROXYINDOLE
Raters disagreehair dyeingCAS 2380-86-1
At least one of our safety lists speaks to this ingredient. Also written as 6 hydroxyindole, 6-Hydroxyindole.
Raters don't agree. Here's where each one stands
Safe
Greenlens Precautionary Screen
Independent
Caution
Greenlens Ingredient Scan
Independent
Greenlens Tolerance Screen
Independent
EU Harmonised Classification (CLP Annex VI)
Government
Concern
—
Where each list lands
Funding shown- Caution
Greenlens Ingredient Scan
Independent
Listed in Annex III of the EU Cosmetics Regulation (ref 209) — allowed only under restrictions. (EU Cosmetics Regulation Annex III (restricted))
- Safe
Greenlens Precautionary Screen
Independent
No listed hazard trait recognized for this ingredient.
- Caution
Greenlens Tolerance Screen
Also screened — not on these lists
- Health Canada Ingredient Hotlist
- California Proposition 65
- US NTP Report on Carcinogens
- IARC Monographs
- ANSES Endocrine Disruptors
- EU Microplastics Restriction
Where regulators stand
Shown side by side, never combinedEach jurisdiction is reported on its own terms, from its own official lists. Where they disagree, that disagreement is the finding. Absence from a list is never a safety claim.
European Union
RestrictedAllowed only under stated conditions or limits.
- European Commission · EU Cosmetics Regulation Annex III (restricted)Listed in Annex III of the EU Cosmetics Regulation (ref 209) — allowed only under restrictions.
- ECHA (EU CLP Regulation) · EU CLP Regulation Annex VI, Table 3 (harmonised classification, ECHA export): Skin Sens. 1Carries an EU harmonised classification (Skin Sens. 1) — a skin sensitiser under CLP Annex VI, index 613-218-00-1. A hazard classification, not proof of harm at the level used.
Canada
No listing foundNot on the lists we hold for this jurisdiction. That is an absence of a listing, not a safety finding.
Checked: Health Canada Cosmetic Ingredient Hotlist.
Notes
- EU harmonised skin sensitizer
- EU-restricted (with limits)
