Ingredient profile
Benzisothiazolinone
Raters disagreeantimicrobialCAS 2634-33-5
At least one of our safety lists speaks to this ingredient. Also written as benzisothiazolinone, BENZISOTHIAZOLINONE.
Raters don't agree. Here's where each one stands
Safe
Greenlens Ingredient Scan
Independent
Greenlens Tolerance Screen
Independent
Caution
Greenlens Precautionary Screen
Independent
EU Harmonised Classification (CLP Annex VI)
Government
Concern
—
Where each list lands
Funding shown- Safe
Greenlens Ingredient Scan
Independent
No EU-regulated hazard recognized for this ingredient.
- Caution
Greenlens Precautionary Screen
Independent
An isothiazolinone preservative and potent contact allergen; not EU-approved for cosmetics. (EU CLP Annex VI (skin sensitiser Cat. 1/1A); ChemSec SIN List (Substitute It Now))
- Safe
Greenlens Tolerance Screen
Also screened — not on these lists
- Health Canada Ingredient Hotlist
- California Proposition 65
- US NTP Report on Carcinogens
- IARC Monographs
- ANSES Endocrine Disruptors
- EU Microplastics Restriction
Where regulators stand
Shown side by side, never combinedEach jurisdiction is reported on its own terms, from its own official lists. Where they disagree, that disagreement is the finding. Absence from a list is never a safety claim.
European Union
FlaggedCarries a formal hazard classification. Not itself a cosmetic use rule.
- ECHA (EU CLP Regulation) · EU CLP Regulation Annex VI, Table 3 (harmonised classification, ECHA export): Skin Sens. 1ACarries an EU harmonised classification (Skin Sens. 1A) — a skin sensitiser under CLP Annex VI, index 613-088-00-6. A hazard classification, not proof of harm at the level used.
Canada
No listing foundNot on the lists we hold for this jurisdiction. That is an absence of a listing, not a safety finding.
Checked: Health Canada Cosmetic Ingredient Hotlist.
California
No listing found
Notes
- Strong contact sensitizer
- EU harmonised skin sensitizer
