Ingredient profile
P-PHENYLENEDIAMINE
hair dyeingCAS 106-50-3
At least one of our safety lists speaks to this ingredient. Also written as p-PHENYLENEDIAMINE, p-Phenylenediamine, p-phenylenediamine…
Where each list lands
Funding shown- Caution
Greenlens Ingredient Scan
Independent
Listed in Annex III of the EU Cosmetics Regulation (ref 8a) — allowed only under restrictions. (EU Cosmetics Regulation Annex III (restricted))
- Caution
Greenlens Precautionary Screen
Independent
A permanent hair-dye ingredient and one of the strongest known contact sensitizers. (ChemSec SIN List (Substitute It Now))
- Caution
Greenlens Tolerance Screen
Independent
Listed in Annex III of the EU Cosmetics Regulation (ref 8a) — allowed only under restrictions. (EU Cosmetics Regulation Annex III (restricted))
- Caution
Health Canada Ingredient Hotlist
Government
A hair-dye ingredient and strong sensitizer: not permitted on skin; capped in oxidative hair dyes. (Health Canada Cosmetic Ingredient Hotlist)
- Caution
ANSES Endocrine Disruptors
Government
An ANSES endocrine-disruptor candidate (SNPE2); an oxidative hair-dye ingredient and strong sensitizer, flagged for endocrine activity. (ANSES — French national strategy on endocrine disruptors (SNPE2))
- Caution
EU Harmonised Classification (CLP Annex VI)
Government
Carries an EU harmonised classification (Skin Sens. 1) — a skin sensitiser under CLP Annex VI, index 612-028-00-6. A hazard classification, not proof of harm at the level used. (EU CLP Regulation Annex VI, Table 3 (harmonised classification, ECHA export))
Also screened — not on these lists
- California Proposition 65
- US NTP Report on Carcinogens
- IARC Monographs
- EU Microplastics Restriction
Where regulators stand
Shown side by side, never combinedEach jurisdiction is reported on its own terms, from its own official lists. Where they disagree, that disagreement is the finding. Absence from a list is never a safety claim.
European Union
RestrictedAllowed only under stated conditions or limits.
- European Commission · EU Cosmetics Regulation Annex III (restricted)Listed in Annex III of the EU Cosmetics Regulation (ref 8a) — allowed only under restrictions.
- ECHA (EU CLP Regulation) · EU CLP Regulation Annex VI, Table 3 (harmonised classification, ECHA export): Skin Sens. 1Carries an EU harmonised classification (Skin Sens. 1) — a skin sensitiser under CLP Annex VI, index 612-028-00-6. A hazard classification, not proof of harm at the level used.
Canada
RestrictedAllowed only under stated conditions or limits.
- Health Canada
Notes
- Strong contact sensitizer
- ANSES endocrine candidate
- EU-restricted (with limits)
- Health Canada Hotlist — restricted
