Spot Defy safety rating

Spot Defy safety rating | Greenlens

Raters split

Ingredient safety

A 60-point gap between the two loudest voices.

40IARC MonographsGovernment

100Greenlens Tolerance ScreenIndependent

050100

See why, ingredient by ingredient

All 1404 cleaner options, safest first We show the best 12, including the strongest on each axis.

Every rater, every axis

Ingredient safety

60 pts apart

A government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
A government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →

Also screened, nothing found: ECHA SVHC Candidate List · California Proposition 65 · ANSES Endocrine Disruptors · EU Harmonised Classification (CLP Annex VI) · Health Canada Ingredient Hotlist

Environmental

Also screened, nothing found: EU Microplastics Restriction

Coverage & match quality

5 ratings · 1 of 4 axes

Some ratings rest on an automatic match that has not been human-reviewed.
Fewer raters reach smaller-brand products, so a missing rating is not a clean bill of health, only a gap.

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Ingredient safety1.0×

Environmentalno rating

No rater covers this axis for this product, so its weight can't move the score.

Laborno rating

No rater covers this axis for this product, so its weight can't move the score.

Packagingno rating

No rater covers this axis for this product, so its weight can't move the score.

0 means ignored. Higher = more weight in your composite.

Ingredients, decoded

Data availability

Robust23 of 23 characterized

Our sources have reference data on all 23 listed ingredients.

Worth a look (2)

Quartzabrasiveraters disagree
NTP known carcinogenflagged by 2 of 9 lists →

What these ingredient tags mean (2)

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

humectantGlycerin, Sodium PCA
- Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
- Sodium PCA: The salt of PCA, one of the water-holding substances the outer layer of skin makes for itself. Dörner C, Steinbinder J, Sachslehner AP, Sukseree S, Eckhart L, "Amino Acid Metabolism of the Skin: Control by Specific Enzymes and Contribution to Protective Functions", Metabolites 2025;15(9):601, DOI 10.3390/metabo15090601, open access, section "Glutamine Is Converted to Pyrrolidone Carboxylic Acid, a Component of the NMF": "pyrrolidone carboxylic acid (PCA), also known as pyroglutamic acid or 5-oxoproline, accumulates in the stratum corneum."
soothingNiacinamide
- Niacinamide: A vitamin B3 form that supports the skin barrier and has anti-inflammatory activity; it turns up in products aimed at acne, rosacea and eczema. Camillo L, Zavattaro E, Savoia P, "Nicotinamide: A Multifaceted Molecule in Skin Health and Beyond", Medicina (Kaunas) 2025;61(2):254, DOI 10.3390/medicina61020254, PMID 40005371, open access: it "is extensively used in ... the treatment of dermatological conditions such as blistering diseases, atopic dermatitis, rosacea, and acne vulgaris", and contributes to reducing inflammation. On the acne evidence specifically: Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F, "Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne", Cochrane Database Syst Rev 2020;5:CD011368, DOI 10.1002/14651858.CD011368.pub2, PMID 32356369, records "low-quality evidence" for every nicotinamide comparison it could pool, and none of its four nicotinamide studies measured the physician global assessment at all.