Deep Hydration 48 Hour Activation Serum safety rating

Deep Hydration 48 Hour Activation Serum safety rating | Greenlens

All 1114 cleaner options, safest first We show the best 12, including the strongest on each axis.

Every rater, every axis

Ingredient safety

raters agree

Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
A government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →

Also screened, nothing found: ECHA SVHC Candidate List · California Proposition 65 · IARC Monographs · ANSES Endocrine Disruptors · US NTP Report on Carcinogens · EU Harmonised Classification (CLP Annex VI)

Environmental

Also screened, nothing found: EU Microplastics Restriction

Labor

Run by a nonprofit. Auto-linked to this product, not yet human-reviewed. This rates Cetaphil as a company and applies to everything they make, not this product alone. Checked this week. about this rater →

Coverage & match quality

5 ratings · 2 of 4 axes

Some ratings rest on an automatic match that has not been human-reviewed.
Fewer raters reach smaller-brand products, so a missing rating is not a clean bill of health, only a gap.

Weighted by what you care about

Tune your weights

composite recomputes live

+

Ingredient safety1.0×

Environmentalno rating

No rater covers this axis for this product, so its weight can't move the score.

Labor1.0×

Packagingno rating

No rater covers this axis for this product, so its weight can't move the score.

0 means ignored. Higher = more weight in your composite.

Ingredients, decoded

Data availability

Robust29 of 29 characterized

Our sources have reference data on all 29 listed ingredients.

Worth a look (3)

Citric Acidfragrance · chelating · bufferingraters disagree
Health Canada Hotlist — restrictedflagged by 1 of 9 lists →

What these ingredient tags mean (3)

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

common irritantPropylene Glycol
- Propylene Glycol: A solvent that shows up in patch-test clinics, more often as irritation than as allergy. American Contact Dermatitis Society, Allergen of the Year 2018 (Jacob SE, Scheman A, McGowan MA, Dermatitis 2018;29(1):3-5).
humectantGlycerin, Hydrolyzed Hyaluronic Acid, Panthenol
- Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
- Hydrolyzed Hyaluronic Acid: A humectant that holds a large amount of water at the skin surface. Chylińska N, Maciejczyk M, "Hyaluronic Acid and Skin: Its Role in Aging and Wound-Healing Processes", Gels 2025;11(4):281, DOI 10.3390/gels11040281, PMID 40277717, open access: hyaluronic acid's "high osmotic activity and anionic structure enable it to bind large amounts of water", and "sodium and potassium hyaluronate are widely used in moisturizing products". The same review notes that high-molecular-weight hyaluronic acid does not penetrate the deeper layers.
- Panthenol: A provitamin B5 humectant used in products aimed at irritated and healing skin. On the humectant half: Ferreira VTP, Silva GC, Martin AA, Maia Campos PMBG, "Topical dexpanthenol effects on physiological parameters of the stratum corneum by Confocal Raman Microspectroscopy", Skin Res Technol 2023;29(9):e13317, DOI 10.1111/srt.13317, PMID 37753694, PMCID PMC10504581, open access, Introduction: "As a humectant, it has been shown to retain water more efficiently than other humectants during the last stages of dehydration..." On the soothing half, which that paper does NOT support: Cho YS, Kim HO, Woo SM, Lee DH, "Use of Dexpanthenol for Atopic Dermatitis—Benefits and Recommendations Based on Current Evidence", J Clin Med 2022;11(14):3943, DOI 10.3390/jcm11143943, PMID 35887707, open access, section 3.5: "To facilitate wound healing, dexpanthenol reduces inflammation, and promotes cell proliferation and epithelial remodeling."
soothingPanthenol
- Panthenol: A provitamin B5 humectant used in products aimed at irritated and healing skin. On the humectant half: Ferreira VTP, Silva GC, Martin AA, Maia Campos PMBG, "Topical dexpanthenol effects on physiological parameters of the stratum corneum by Confocal Raman Microspectroscopy", Skin Res Technol 2023;29(9):e13317, DOI 10.1111/srt.13317, PMID 37753694, PMCID PMC10504581, open access, Introduction: "As a humectant, it has been shown to retain water more efficiently than other humectants during the last stages of dehydration..." On the soothing half, which that paper does NOT support: Cho YS, Kim HO, Woo SM, Lee DH, "Use of Dexpanthenol for Atopic Dermatitis—Benefits and Recommendations Based on Current Evidence", J Clin Med 2022;11(14):3943, DOI 10.3390/jcm11143943, PMID 35887707, open access, section 3.5: "To facilitate wound healing, dexpanthenol reduces inflammation, and promotes cell proliferation and epithelial remodeling."