SkinMedica
HA5 Hydra Collagen Replenish + Restore Hydrator
uncategorized
Cleaner pick · Safest moisturizers we have rated
Anua US
Barrier Reboot Daily Moisturizer$24
Ingredient safetyRaters agree
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All 735 cleaner options, safest first We show the best 12, including the strongest on each axis.
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Ingredient safety
raters agreeA government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Also screened, nothing found: California Proposition 65 · IARC Monographs · US NTP Report on Carcinogens · ANSES Endocrine Disruptors · ECHA SVHC Candidate List · Health Canada Ingredient Hotlist
Environmental
Also screened, nothing found: EU Microplastics Restriction
Coverage & match quality
4 ratings · 1 of 4 axes
- Some ratings rest on an automatic match that has not been human-reviewed.
- Fewer raters reach smaller-brand products, so a missing rating is not a clean bill of health, only a gap.
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Environmentalno rating
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Laborno rating
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Ingredients, decoded
Data availability
Robust42 of 42 characterized
Our sources have reference data on all 42 listed ingredients.
Worth a look (1)
EU harmonised skin sensitizerflagged by 2 of 9 lists
No flags in our sources (41)
- Water
- Glycerinhumectant
- Caprylic/Capric Triglyceride
- Shorea Stenoptera Seed Butter
- C9-12 Alkane
- Propanediol
- Linoleic Acidbarrier lipid
- Sodium Acrylates Copolymer
- Passiflora Edulis Seed Oil
- Sodium Hyaluronatehumectant
- Hydrolyzed Hyaluronic Acidhumectant
- Sodium Hyaluronate Crosspolymer
- Nelumbo Nucifera Germ Extract
- Collagen
- Butyl Avocadate
- Trehalose
- Serine
- Vitis Vinifera Flower Cell Extract
- Linolenic Acid
- Ureahumectant
- Caprylhydroxamic Acid
- Algin
- Polyglutamic Acid
- Tocopherol
- Oleic Acid
- Pullulan
- Palmitic Acid
- Glyceryl Glucoside
- Coco-Caprylate/Caprate
- Lecithin
- 1,2-Hexanediol
- Pentylene Glycol
- Stearic Acid
- Benzoic Acid
- Caprylyl Glycol
- Polysorbate 20
- Dehydroacetic Acid
- Glyceryl Polyacrylate
- Potassium Phosphate
- Disodium Phosphate
- Sodium Benzoate
What these ingredient tags mean (3)
These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.
fragrance materialBenzyl Alcohol
- Benzyl Alcohol: Used both as a fragrance component and as a preservative; the EU names it either way. EU Regulation (EC) 1223/2009, Annex III entry 45: a fragrance substance whose presence must be indicated in the list of ingredients above 0,001% in leave-on and 0,01% in rinse-off products, because of established contact-allergy risk. That entry carries transition footnote (38), which is footnote (37) plus a condition: stock that does not comply may still be made available until 31 July 2028 only "provided that they comply with the restrictions applicable on 15 August 2023", and only if it was lawfully placed on the Union market before the 31 July 2026 cut-off. Entry 45 covers its non-preservative use; it is separately an allowed preservative at Annex V entry 34.
humectantGlycerin, Sodium Hyaluronate, Urea
- Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
- Sodium Hyaluronate: A humectant that holds a large amount of water at the skin surface. Chylińska N, Maciejczyk M, "Hyaluronic Acid and Skin: Its Role in Aging and Wound-Healing Processes", Gels 2025;11(4):281, DOI 10.3390/gels11040281, PMID 40277717, open access: hyaluronic acid's "high osmotic activity and anionic structure enable it to bind large amounts of water", and "sodium and potassium hyaluronate are widely used in moisturizing products". The same review notes that high-molecular-weight hyaluronic acid does not penetrate the deeper layers.
- Urea: A humectant the skin already makes; at higher levels it also softens thickened skin. StatPearls, "Moisturizers", NCBI Bookshelf NBK545171, updated 12 February 2024: "Urea is a component of NMF. The addition of urea to moisturizers helps with the absorption of water into the stratum corneum." The FDA label for prescription-strength urea calls it keratolytic and states that its mechanism of action is not yet known.
barrier lipidLinoleic Acid
- Linoleic Acid: An essential fatty acid the skin barrier uses and cannot make for itself. Khnykin D, Miner JH, Jahnsen F, "Role of fatty acid transporters in epidermis", Dermatoendocrinol 2011;3(2):53-61, DOI 10.4161/derm.3.2.14816, open access: "The human body can produce all but two of the fatty acids it needs: linoleic acid (C18:2, n6) and alpha-linolenic acid (C18:3, n3)", and replacing linoleic acid with a non-essential fatty acid "will lead to barrier defects". Feingold and Elias, J Lipid Res 2024: linoleate "is required for the synthesis of a subgroup of acylceramides".