Hydrating Gel-to-Cream Facial Cleanser

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

• common irritantCocamidopropyl Betaine

  • Cocamidopropyl Betaine: A mild cleansing agent, but a recurring patch-test finding, usually traced to leftovers from how it is made. American Contact Dermatitis Society, Allergen of the Year 2004 (Fowler JF Jr, Dermatitis 2004;15(1):3-4).

• exfoliating acidLactic Acid

  • Lactic Acid: An alpha hydroxy acid that loosens surface skin cells; it also makes skin more sun-sensitive while you use it. FDA, "Guidance for Industry: Labeling for Topically Applied Cosmetic Products Containing Alpha Hydroxy Acids as Ingredients" (announced at 70 FR 1721, 10 January 2005; FDA web pages title it "Labeling for Cosmetics Containing Alpha Hydroxy Acids"), which names this acid and recommends the statement "Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn."

• humectantGlycerin, Sodium PCA

  • Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
  • Sodium PCA: The salt of PCA, one of the water-holding substances the outer layer of skin makes for itself. Dörner C, Steinbinder J, Sachslehner AP, Sukseree S, Eckhart L, "Amino Acid Metabolism of the Skin: Control by Specific Enzymes and Contribution to Protective Functions", Metabolites 2025;15(9):601, DOI 10.3390/metabo15090601, open access, section "Glutamine Is Converted to Pyrrolidone Carboxylic Acid, a Component of the NMF": "pyrrolidone carboxylic acid (PCA), also known as pyroglutamic acid or 5-oxoproline, accumulates in the stratum corneum."

• barrier lipidLinoleic Acid

  • Linoleic Acid: An essential fatty acid the skin barrier uses and cannot make for itself. Khnykin D, Miner JH, Jahnsen F, "Role of fatty acid transporters in epidermis", Dermatoendocrinol 2011;3(2):53-61, DOI 10.4161/derm.3.2.14816, open access: "The human body can produce all but two of the fatty acids it needs: linoleic acid (C18:2, n6) and alpha-linolenic acid (C18:3, n3)", and replacing linoleic acid with a non-essential fatty acid "will lead to barrier defects". Feingold and Elias, J Lipid Res 2024: linoleate "is required for the synthesis of a subgroup of acylceramides".