REVEAL Biomimetic Peel Pads with LSR10

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

• commonly dryingHAMAMELIS VIRGINIANA EXTRACT, ALCOHOL DENAT

  • HAMAMELIS VIRGINIANA EXTRACT: A tannin-rich astringent; the distillate sold under this name usually carries added alcohol, which is where the dry finish comes from. United States Pharmacopeia monograph "Witch Hazel", USP-NF version 02_01, DOI 10.31003/USPNF_M89070_02_01. The public DOI landing page carries a 2018 copyright and shows the definition, "Witch Hazel is a clear, colorless distillate prepared from recently cut and partially dried dormant twigs of Hamamelis virginiana L."; the specification, a distillate to which "150 mL of alcohol" is added per 850 mL at 14,0% to 15,0% ethanol, sits behind the USP subscription paywall. The monograph governs the pharmacopoeial article, not every product that prints this INCI name.
  • ALCOHOL DENAT: Denatured ethanol: a fast-evaporating solvent that thins a formula and leaves a dry finish. International Chemical Safety Card ICSC 0044, Ethanol (anhydrous), prepared by an international group of experts for the ILO and WHO: "The substance defats the skin, which may cause dryness or cracking." WHO Guidelines on Hand Hygiene in Health Care (2009) records depletion of the skin lipid barrier by lipid-dissolving alcohols, and also that "the lipid-dissolving effect of alcohols is inversely related to their concentration". Both describe stronger exposures than a cosmetic formula.

• exfoliating acidLACTIC ACID

  • LACTIC ACID: An alpha hydroxy acid that loosens surface skin cells; it also makes skin more sun-sensitive while you use it. FDA, "Guidance for Industry: Labeling for Topically Applied Cosmetic Products Containing Alpha Hydroxy Acids as Ingredients" (announced at 70 FR 1721, 10 January 2005; FDA web pages title it "Labeling for Cosmetics Containing Alpha Hydroxy Acids"), which names this acid and recommends the statement "Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn."

• humectantGLYCERIN, UREA, SODIUM PCA

  • GLYCERIN: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
  • UREA: A humectant the skin already makes; at higher levels it also softens thickened skin. StatPearls, "Moisturizers", NCBI Bookshelf NBK545171, updated 12 February 2024: "Urea is a component of NMF. The addition of urea to moisturizers helps with the absorption of water into the stratum corneum." The FDA label for prescription-strength urea calls it keratolytic and states that its mechanism of action is not yet known.
  • SODIUM PCA: The salt of PCA, one of the water-holding substances the outer layer of skin makes for itself. Dörner C, Steinbinder J, Sachslehner AP, Sukseree S, Eckhart L, "Amino Acid Metabolism of the Skin: Control by Specific Enzymes and Contribution to Protective Functions", Metabolites 2025;15(9):601, DOI 10.3390/metabo15090601, open access, section "Glutamine Is Converted to Pyrrolidone Carboxylic Acid, a Component of the NMF": "pyrrolidone carboxylic acid (PCA), also known as pyroglutamic acid or 5-oxoproline, accumulates in the stratum corneum."

• soothingALLANTOIN

  • ALLANTOIN: A skin protectant used at low levels in products aimed at irritated skin. FDA OTC skin protectant monograph, 21 CFR 347.10(a), lists allantoin as a skin-protectant active at 0,5 to 2%. Its labelled indications are 21 CFR 347.50(b)(1), "temporarily protects minor: cuts, scrapes, burns", and (b)(2), which covers chafed, chapped or cracked skin. The monograph does not give it the "minor skin irritation and itching" wording; that one belongs to colloidal oatmeal, sodium bicarbonate and one combination, and to topical starch without the itching half.