Beauty Sémillon Overnight Retinol Serum safety rating

Beauty Sémillon Overnight Retinol Serum safety rating | Greenlens

Raters split

Ingredient safety

A 33-point gap between the two loudest voices.

65California Proposition 65Government

98Greenlens Precautionary ScreenIndependent

050100

See why, ingredient by ingredient

All 2001 cleaner options, safest first We show the best 12, including the strongest on each axis.

Every rater, every axis

Ingredient safety

33 pts apart

Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
A government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
A government authority. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →

Also screened, nothing found: ANSES Endocrine Disruptors · ECHA SVHC Candidate List · US NTP Report on Carcinogens · EU Harmonised Classification (CLP Annex VI) · IARC Monographs

Environmental

Also screened, nothing found: EU Microplastics Restriction

Labor

Run by a nonprofit. Auto-linked to this product, not yet human-reviewed. Checked this week. about this rater →

Coverage & match quality

6 ratings · 2 of 4 axes

Some ratings rest on an automatic match that has not been human-reviewed.
Fewer raters reach smaller-brand products, so a missing rating is not a clean bill of health, only a gap.

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Ingredient safety1.0×

Environmentalno rating

No rater covers this axis for this product, so its weight can't move the score.

Labor1.0×

Packagingno rating

No rater covers this axis for this product, so its weight can't move the score.

0 means ignored. Higher = more weight in your composite.

Ingredients, decoded

Data availability

Robust19 of 19 characterized

Our sources have reference data on all 19 listed ingredients.

Worth a look (3)

Retinolretinoidskin conditioningraters disagree

What these ingredient tags mean (3)

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

retinoidRetinol
- Retinol: A vitamin A derivative that speeds skin turnover; dryness and flaking while skin adjusts are its usual accompaniment. SCCS Opinion on Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate), SCCS/1576/16, final version of 6 October 2016; Commission Regulation (EU) 2024/996 added the group to EU Regulation (EC) 1223/2009 Annex III entry 376, capping it at 0,05% retinol equivalent in body lotion and 0,3% in other leave-on and rinse-off products, with the label statement "Contains Vitamin A. Consider your daily intake before use."
humectantSodium Hyaluronate, Glycerin
- Sodium Hyaluronate: A humectant that holds a large amount of water at the skin surface. Chylińska N, Maciejczyk M, "Hyaluronic Acid and Skin: Its Role in Aging and Wound-Healing Processes", Gels 2025;11(4):281, DOI 10.3390/gels11040281, PMID 40277717, open access: hyaluronic acid's "high osmotic activity and anionic structure enable it to bind large amounts of water", and "sodium and potassium hyaluronate are widely used in moisturizing products". The same review notes that high-molecular-weight hyaluronic acid does not penetrate the deeper layers.
- Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
soothingNiacinamide
- Niacinamide: A vitamin B3 form that supports the skin barrier and has anti-inflammatory activity; it turns up in products aimed at acne, rosacea and eczema. Camillo L, Zavattaro E, Savoia P, "Nicotinamide: A Multifaceted Molecule in Skin Health and Beyond", Medicina (Kaunas) 2025;61(2):254, DOI 10.3390/medicina61020254, PMID 40005371, open access: it "is extensively used in ... the treatment of dermatological conditions such as blistering diseases, atopic dermatitis, rosacea, and acne vulgaris", and contributes to reducing inflammation. On the acne evidence specifically: Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F, "Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne", Cochrane Database Syst Rev 2020;5:CD011368, DOI 10.1002/14651858.CD011368.pub2, PMID 32356369, records "low-quality evidence" for every nicotinamide comparison it could pool, and none of its four nicotinamide studies measured the physician global assessment at all.