Prime and Fine, Smoothing Refiner

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

• comedogenic in testingISOPROPYL PALMITATE

  • ISOPROPYL PALMITATE: A light emollient named among the pore-clogging materials in the rabbit-ear assay. Fulton JE Jr, Pay SR, Fulton JE 3rd, "Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear", J Am Acad Dermatol 1984;10(1):96-105, PMID 6229554. The openly readable abstract names this ingredient among its "ingredient offenders", in prose and without a numeric rating: "Ingredient offenders include isopropyl myristate and its analogs, such as isopropyl palmitate, isopropyl isostearate, butyl stearate, isostearyl neopentanoate, myristyl myristate..." The rabbit-ear assay rates raw ingredients and does not predict how a finished formula behaves on human skin.

• common irritantLANOLIN

  • LANOLIN: A rich wool-derived emollient that is also a long-standing patch-test allergen. American Contact Dermatitis Society, Allergen of the Year 2023: "Lanolin: The 2023 American Contact Dermatitis Society Allergen of the Year", Cutis 2023;112(2):78-81, DOI 10.12788/cutis.0825, PMID 37820332; FDA OTC skin protectant monograph, 21 CFR 347.10(k), lists lanolin as a skin protectant at 12,5 to 50%.

• rich occlusiveLANOLIN

  • LANOLIN: A rich wool-derived emollient that is also a long-standing patch-test allergen. American Contact Dermatitis Society, Allergen of the Year 2023: "Lanolin: The 2023 American Contact Dermatitis Society Allergen of the Year", Cutis 2023;112(2):78-81, DOI 10.12788/cutis.0825, PMID 37820332; FDA OTC skin protectant monograph, 21 CFR 347.10(k), lists lanolin as a skin protectant at 12,5 to 50%.