Apple Fresh

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

• common irritantSodium Lauryl Sulfate, Cocamidopropyl Betaine, Propylene Glycol

  • Sodium Lauryl Sulfate: A strong cleansing agent used as the reference irritant in skin-irritation testing. OECD Test Guideline 439 (in vitro skin irritation, reconstructed human epidermis), paragraph 24: "The suggested PC is 5% aqueous SDS", sodium dodecyl sulphate, the same substance as sodium lauryl sulfate, CAS 151-21-3.
  • Cocamidopropyl Betaine: A mild cleansing agent, but a recurring patch-test finding, usually traced to leftovers from how it is made. American Contact Dermatitis Society, Allergen of the Year 2004 (Fowler JF Jr, Dermatitis 2004;15(1):3-4).
  • Propylene Glycol: A solvent that shows up in patch-test clinics, more often as irritation than as allergy. American Contact Dermatitis Society, Allergen of the Year 2018 (Jacob SE, Scheman A, McGowan MA, Dermatitis 2018;29(1):3-5).

• undeclared fragrance blendParfum

  • Parfum: A blend the label does not itemize, so what is in it cannot be read from the ingredient list. EU Regulation (EC) 1223/2009 permits the collective term "parfum"; the SCCS Opinion on Fragrance Allergens (SCCS/1459/11) reviews the contact-allergy evidence for the substances it can contain.

• rich occlusiveDimethicone

  • Dimethicone: A silicone that forms a film on the surface of the skin without an oily feel. FDA OTC skin protectant monograph, 21 CFR 347.10(g), lists dimethicone as a skin protectant at 1 to 30%.

• humectantPanthenol

  • Panthenol: A provitamin B5 humectant used in products aimed at irritated and healing skin. On the humectant half: Ferreira VTP, Silva GC, Martin AA, Maia Campos PMBG, "Topical dexpanthenol effects on physiological parameters of the stratum corneum by Confocal Raman Microspectroscopy", Skin Res Technol 2023;29(9):e13317, DOI 10.1111/srt.13317, PMID 37753694, PMCID PMC10504581, open access, Introduction: "As a humectant, it has been shown to retain water more efficiently than other humectants during the last stages of dehydration..." On the soothing half, which that paper does NOT support: Cho YS, Kim HO, Woo SM, Lee DH, "Use of Dexpanthenol for Atopic Dermatitis—Benefits and Recommendations Based on Current Evidence", J Clin Med 2022;11(14):3943, DOI 10.3390/jcm11143943, PMID 35887707, open access, section 3.5: "To facilitate wound healing, dexpanthenol reduces inflammation, and promotes cell proliferation and epithelial remodeling."

• soothingNiacinamide, Panthenol

  • Niacinamide: A vitamin B3 form that supports the skin barrier and has anti-inflammatory activity; it turns up in products aimed at acne, rosacea and eczema. Camillo L, Zavattaro E, Savoia P, "Nicotinamide: A Multifaceted Molecule in Skin Health and Beyond", Medicina (Kaunas) 2025;61(2):254, DOI 10.3390/medicina61020254, PMID 40005371, open access: it "is extensively used in ... the treatment of dermatological conditions such as blistering diseases, atopic dermatitis, rosacea, and acne vulgaris", and contributes to reducing inflammation. On the acne evidence specifically: Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F, "Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne", Cochrane Database Syst Rev 2020;5:CD011368, DOI 10.1002/14651858.CD011368.pub2, PMID 32356369, records "low-quality evidence" for every nicotinamide comparison it could pool, and none of its four nicotinamide studies measured the physician global assessment at all.
  • Panthenol: A provitamin B5 humectant used in products aimed at irritated and healing skin. On the humectant half: Ferreira VTP, Silva GC, Martin AA, Maia Campos PMBG, "Topical dexpanthenol effects on physiological parameters of the stratum corneum by Confocal Raman Microspectroscopy", Skin Res Technol 2023;29(9):e13317, DOI 10.1111/srt.13317, PMID 37753694, PMCID PMC10504581, open access, Introduction: "As a humectant, it has been shown to retain water more efficiently than other humectants during the last stages of dehydration..." On the soothing half, which that paper does NOT support: Cho YS, Kim HO, Woo SM, Lee DH, "Use of Dexpanthenol for Atopic Dermatitis—Benefits and Recommendations Based on Current Evidence", J Clin Med 2022;11(14):3943, DOI 10.3390/jcm11143943, PMID 35887707, open access, section 3.5: "To facilitate wound healing, dexpanthenol reduces inflammation, and promotes cell proliferation and epithelial remodeling."