PDRN Essence 100 safety rating

PDRN Essence 100 safety rating | Greenlens

Every rater, every axis

Ingredient safety

raters agree

Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. We started showing this score on Sep 8, 2026. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. We started showing this score on Sep 8, 2026. about this rater →
Independent — not funded by the brands it rates. Auto-linked to this product, not yet human-reviewed. Checked this week. We started showing this score on Sep 8, 2026. about this rater →

Also screened, nothing found: ANSES Endocrine Disruptors · ECHA SVHC Candidate List · California Proposition 65 · US NTP Report on Carcinogens · EU Harmonised Classification (CLP Annex VI) · Health Canada Ingredient Hotlist · IARC Monographs

We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026. We started showing this clearance on Sep 8, 2026.

Environmental

Also screened, nothing found: EU Microplastics Restriction

We started showing this clearance on Sep 8, 2026.

Coverage & match quality

3 ratings · 1 of 4 axes

Some ratings rest on an automatic match that has not been human-reviewed.
Fewer raters reach smaller-brand products, so a missing rating is not a clean bill of health, only a gap.

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Ingredient safety1.0×

Environmentalno rating

No rater covers this axis for this product, so its weight can't move the score.

Laborno rating

No rater covers this axis for this product, so its weight can't move the score.

Packagingno rating

No rater covers this axis for this product, so its weight can't move the score.

0 means ignored. Higher = more weight in your composite.

Ingredients, decoded

Data availability

Robust11 of 12 characterized

Our sources have reference data on 11 of 12 listed ingredients; 1 is uncharacterized in our data — a gap, not a clean bill.

No flags in our sources (11)

No data in our sources (1)

1,2-Hexanedio

Not a verdict — our authorities simply have no reference for these.

What these ingredient tags mean (3)

These describe what an ingredient is, not whether it is a problem. The stance marks above are the ratings; these are not.

comedogenic in testingIsopropyl Myristate
- Isopropyl Myristate: A light emollient, and the ester the rabbit-ear literature names first. Fulton JE Jr, Pay SR, Fulton JE 3rd, "Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear", J Am Acad Dermatol 1984;10(1):96-105, PMID 6229554. The openly readable abstract names this ingredient among its "ingredient offenders", in prose and without a numeric rating: "Ingredient offenders include isopropyl myristate and its analogs, such as isopropyl palmitate, isopropyl isostearate, butyl stearate, isostearyl neopentanoate, myristyl myristate..." The rabbit-ear assay rates raw ingredients and does not predict how a finished formula behaves on human skin.
humectantGlycerin
- Glycerin: A humectant, and one of the two ingredients a comparison of moisturiser components found made a significant difference to skin hydration. FDA OTC skin protectant monograph, 21 CFR 347.10(h), lists glycerin as a skin protectant at 20 to 45%. On the humectant half: Jeong CB, Han JY, Cho JC, Suh KD, Nam GW, "Analysis of electrical property changes of skin by oil-in-water emulsion components", Int J Cosmet Sci 2013;35(4):402-410, DOI 10.1111/ics.12059, PMID 23621673, found that "glycerine and urea showed significant skin hydration effects compared with other humectants".
soothingNiacinamide
- Niacinamide: A vitamin B3 form that supports the skin barrier and has anti-inflammatory activity; it turns up in products aimed at acne, rosacea and eczema. Camillo L, Zavattaro E, Savoia P, "Nicotinamide: A Multifaceted Molecule in Skin Health and Beyond", Medicina (Kaunas) 2025;61(2):254, DOI 10.3390/medicina61020254, PMID 40005371, open access: it "is extensively used in ... the treatment of dermatological conditions such as blistering diseases, atopic dermatitis, rosacea, and acne vulgaris", and contributes to reducing inflammation. On the acne evidence specifically: Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F, "Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne", Cochrane Database Syst Rev 2020;5:CD011368, DOI 10.1002/14651858.CD011368.pub2, PMID 32356369, records "low-quality evidence" for every nicotinamide comparison it could pool, and none of its four nicotinamide studies measured the physician global assessment at all.